The first results of the Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes (ACCORD-MIND) study appear online today in The Lancet Neurology.
“We know that people with type 2 diabetes have a much higher risk of dementia and memory loss than people without diabetes,” said Jeff D. Williamson, M.D., chief of the Department of Geriatrics and Gerontology and principal investigator of the study”s coordinating center at Wake Forest Baptist. “What we didn”t know was, if you intensively control blood sugar levels in people who have had a history of trouble controlling them, does the added cost and effort to control blood sugar result in a slowed rate of memory loss? After conducting this study, there remains no evidence that it does.
“We also learned, however, that the intensive blood sugar control does preserve brain volume,” added Williamson, director of the Roena Kulynych Center for Memory and Cognition Research at Wake Forest Baptist. “What that means for the long term preservation of cognitive function of these patients, we”re still trying to figure out.”
The ACCORD-MIND trial is a national study sponsored by the National Heart Lung and Blood Institute – part of the National Institutes of Health – designed to examine the effects of different glucose-lowering strategies on the risk for cardiovascular disease.
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